A Synthetic Approach to Ervatamine-Silicine Alkaloids. Enantioselective Total Synthesis of (−)-16-Episilicine
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https://figshare.com/articles/dataset/A_Synthetic_Approach_to_Ervatamine_Silicine_Alkaloids_Enantioselective_Total_Synthesis_of_16_Episilicine/2803096
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资源简介:
Starting from an appropriate unsaturated phenylglycinol-derived oxazolopiperidone lactam, the synthesis of (−)-16-episilicine is reported, the key steps being a stereoselective conjugate addition, a stereoselective alkylation, and a ring-closing metathesis reaction. This represents the first enantioselective total synthesis of an alkaloid of the silicine group.
创建时间:
2016-02-25



