The discovery of novel, potent and highly selective inhibitors of inducible nitric oxide synthase (iNOS)

The discovery of novel, potent and highly selective inhibitors of inducible nitric oxide synthase (iNOS) Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, NITRIC OXIDE SYNTHASE, INDUCIBLE, ... Authors: Cheshire, D.R, Andrews, G, Beaton, H.G, Birkinshaw, T, Boughton-Smith, N, Connolly, S, Cook, T.R, Cooper, A, Cooper, S.L, Cox, D, Dixon, J, Gensmantel, N, Hamley, P.J, Harrison, R, Hartopp, P, Kack, H, Luker, T, Mete, A, Millichip, I, Nicholls, D.J, Pimm, A.D, St-Gallay, S.A, Wallace, A.V. Deposit date: 2014-08-19 Release date: 2014-10-08 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (3 Å) Cite: The Discovery of Novel, Potent and Highly Selective Inhibitors of Inducible Nitric Oxide Synthase (Inos). Bioorg.Med.Chem.Lett., 21, 2011诱导型一氧化氮合酶（inducible nitric oxide synthase, iNOS）新型、强效且高选择性抑制剂的发现 描述：5,6,7,8-四氢生物蝶呤（5,6,7,8-TETRAHYDROBIOPTERIN）、一氧化氮合酶、诱导型…… 作者：Cheshire, D.R、Andrews, G、Beaton, H.G、Birkinshaw, T、Boughton-Smith, N、Connolly, S、Cook, T.R、Cooper, A、Cooper, S.L、Cox, D、Dixon, J、Gensmantel, N、Hamley, P.J、Harrison, R、Hartopp, P、Kack, H、Luker, T、Mete, A、Millichip, I、Nicholls, D.J、Pimm, A.D、St-Gallay, S.A、Wallace, A.V 存档日期：2014-08-19 发布日期：2014-10-08 最后修改日期：2024-11-20 实验方法：X射线衍射（X-RAY DIFFRACTION）（3 Å） 引用文献：《诱导型一氧化氮合酶新型、强效且高选择性抑制剂的发现》，发表于《Bioorg.Med.Chem.Lett.》第21卷，2011年