Role of MPK4 in pathogen-associated molecular pattern-triggered alternative splicing in Arabidopsis. Role of MPK4 in pathogen-associated molecular pattern-triggered alternative splicing in Arabidopsis

Alternative splicing (AS) of pre-mRNAs in plants is an important mechanism of gene regulation in environmental stress tolerance but plant signals involved are essentially unknown. Pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) is mediated by mitogen-activated protein kinases and the majority of PTI defense genes are regulated by MPK3, MPK4 and MPK6. These responses have been mainly analyzed at the transcriptional level, however many splicing factors are direct targets of MAPKs. Here, we studied alternative splicing induced by the PAMP flagellin in Arabidopsis. Overall design: Using RNA-seq to study the Col-0 and summ2 mpk4 Transcriptomes