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thrombin in complex with an oxazolopyridine inhibitor 21

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Protein Data Bank Japan2024-10-09 更新2026-03-21 收录
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https://pdbj.org/mine/summary/1zgi
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thrombin in complex with an oxazolopyridine inhibitor 21 Descriptor: (R)-2-(2-(1H-1,2,4-TRIAZOL-1-YL)BENZYL)-N-(2,2-DIFLUORO-2-(PIPERIDIN-2-YL)ETHYL)OXAZOLO[4,5-C]PYRIDIN-4-AMINE, Hirudin, Thrombin Authors: Deng, J.Z, McMasters, D.R, Rabbat, P.M, Williams, P.D, Coburn, C.A, Yan, Y, Kuo, L.C, Lewis, S.D, Lucas, B.J, Krueger, J.A, Strulovici, B, Vacca, J.P, Lyle, T.A, Burgey, C.S. Deposit date: 2005-04-21 Release date: 2005-09-27 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Development of an oxazolopyridine series of dual thrombin/factor Xa inhibitors via structure-guided lead optimization. Bioorg.Med.Chem.Lett., 15, 2005
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2005-04-21
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