Growth inhibition of KB and its drug-resistant cells by Malformin C and anti-cancer drugs.

Note: Values were means ± SD from more than three independent experiments, with each data point done in duplicate, and all the cells were exposed to different drugs for 72 hours. MDR, multidrug resistance; MRP, multidrug resistance protein; CPT, camptothecin; VP-16, etoposide; Topo I, topoisomerase I; Topo II, topoisomerase II. Malformin C was 233-fold resistant to KB-MDR cells than KB cells (PGrowth inhibition of KB and its drug-resistant cells by Malformin C and anti-cancer drugs.