A molybdenum Schiff base complex: repairing activity on orthodontics-related root absorption by reducing the TNF-α releasing

The reaction between [MoO2(acac)2] and an ONO type Schiff-base ligand (L=(E)-4-bromo-2-(((2-hydroxyphenyl)imino)methyl)phenol) resulted a new oligomer molybdenum complex ([MoO2(L)]n). The oligomer complex was characterized by elemental analysis and FT-IR. The promotion ability of the compound on the osteoblast was measured with Cell Counting Kit-8 assay. The ELISA detection was performed to detect the TNF-α content released by the osteoblast. The activity of the complex to the protein is estimated and investigated by performing the molecular docking simulation.