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Sequencing of cancer autopsies and ctDNA

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NIAID Data Ecosystem2026-03-12 收录
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Tumor heterogeneity is a major obstacle for precision oncology strategies. To characterize inter-lesion heterogeneity in pre-treated cancers, we performed genetic and transcriptomic profiling of synchronous lesions from ten rapid autopsies comprising six cases of breast cancer, three of cholangiocarcinoma and one lung cancer case. For nine patients, we studied mutation representation in circulating cell-free DNA (cfDNA).EGA study EGAS00001005109

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2021-03-23
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