ATG7 Loss in Microglia: Impaired UPR, Increased Oxidative Stress, Less Control of Amyloid Pathology
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https://www.ncbi.nlm.nih.gov/sra/SRP553968
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资源简介：
Microglia contain amyloid-beta (Ab) plaques in Alzheimer's Disease (AD). In an AD mouse model, microglial Atg7 deletion impaired plaque coverage, increasing Ab diffusion and neurotoxicity. This was linked to reduced unfolded protein response, increased oxidative stress, and ferroptosis of microglia.
创建时间：
2025-02-27
