Copper(I)-Catalyzed N–O Bond Formation through Vinyl Nitrene Mediated Pathway under Mild Conditions

Copper­(I)-catalyzed N–O bond formation reactions through vinyl nitrene-mediated pathway were described. The reactions of N-alkoxylbenzamides and 2H-azirines afforded α-amino oxime ethers in good to excellent yields at room temperature, which involved the cleavage of C–N and N–O bonds and the construction of new N–O and C–N bonds. It offers an efficient, regio- and stereoselective synthetic route for α-amino oxime ethers.