Gene expression profile of IL4I1 knockout CAS-1 glioblastoma cells
收藏NIAID Data Ecosystem2026-03-12 收录
下载链接：
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE149910
下载链接
链接失效反馈官方服务：
资源简介：
Aryl hydrocarbon receptor (AHR) activation by tryptophan (Trp) catabolites enhances tumor malignancy and suppresses anti-tumor immunity. Hitherto, indoleamine-2,3-dioxygenase 1 (IDO1) or tryptophan- 2, 3-dioxygenase (TDO2) are recognized as the main Trp-catabolizing enzymes (TCEs) responsible for the generation of AHR agonists. Here, the ability of the aromatic L-amino acid oxidase, interleukin 4 induced 1 (IL4I1), to activate the AHR was investigated using IL4I1 knockout CAS-1 glioblastoma cells. Expression profile of IL4I1 knockout (KO, sgIL4I1-2.4) CAS-1 cells, was compared to the expression profile of non-targeting control (NTC, sgCtrl) or NTC.01 (sgCtrl.01) CAS-1 cells, cultured for 72 h (n = 6). n values represent independent experiments.
创建时间：
2020-11-18
