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Long range spreading of dosage compensation in Drosophila captures transcribed autosomal genes inserted on X

ChEBI2009-08-20 更新2026-07-21 收录

剂量补偿

染色体插入基因转录

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-17729 数据链接链接失效反馈

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资源简介：

Long range spreading of dosage compensation in Drosophila captures transcribed autosomal genes inserted on X

应用场景：

创建时间：

2009-08-20

剂量补偿

染色质结合位点定位

Among organisms with chromosome-based mechanisms of sex determination, failure to equalize expression of X-linked genes between the sexes is typically lethal. In C. elegans, XX hermaphrodites halve tr

NIAID Data Ecosystem50

Ectopically expressed MSL2 females compared with normal females

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果蝇遗传调控

We used H83M2 P element to ectopically expressed MSL2 protein in females to test if the novel formed MSL complex is the directly reason of dosage compensation Overall design: Compare the MSL2 females

NIAID Data Ecosystem40

Examination of DPY-30, DPY-27, SDC-3, DPY-26, MIX-1, SMC-4, ASH-2, RNA Polymerase II binding in wild type and DCC mutant embryos

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染色质分析

Here we exploit the essential process of X-chromosome dosage compensation to elucidate basic mechanisms that control the assembly, genome-wide binding, and function of gene regulatory complexes that

NIAID Data Ecosystem20

Binding of an X-specific condensin correlates with a reduction in active histone modifications at gene regulatory elements. Binding of an X-specific condensin correlates with a reduction in active histone modifications at gene regulatory elements

剂量补偿

表观遗传调控

Condensins are evolutionarily conserved protein complexes that are required for chromosome segregation during cell division and genome organization during interphase. In C. elegans, a specialized cond

NIAID Data Ecosystem40

Sequence variation within similar cis-elements promotes context-specific functions of two Drosophila GA-binding transcription factors (ChIP-seq data set)

转录因子结合位点分析

剂量补偿

A key model for understanding how large transcription complexes are targeted is the Drosophila dosage compensation system in which the Male-Specific Lethal (MSL) transcription complex specifically ide

NIAID Data Ecosystem30

Long range spreading of dosage compensation in Drosophila captures transcribed autosomal genes inserted on X

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