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WGS of Plasmodium falciparum selected with DHODH inhibitors

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NIAID Data Ecosystem2026-03-12 收录
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In vitro resistance selections were performed to characterize the pathways to resistance for antimalarial compound TCMDC-125334. A secondary set of selections were performed to determine whether parasites develop resistance in the context of combined treatment with DSM265 and TCMDC-125334. Both compounds are known inhibitors of PfDHODH.

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2021-01-04
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