Identification of antibodies targeting desired epitopes
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https://www.ncbi.nlm.nih.gov/sra/DRP011590
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资源简介：
To assess the feasibility of an antigen/antibody co-display system for epitope binning, a qAb library consisting of 14 single-chain fragments was displayed on the surface of antigen-expressing mammalian cells. The library underwent interaction with an exogenous reference antibody (rAb), after which the rAb-non-binding cells were sorted using FACS. DNA sequencing of these sorted cells enabled the identification of qAbs targeting an epitope similar to that of the rAb.
创建时间：
2024-05-22
