Hedgehog receptor Patched (PTCH1) in complex with conformation selective nanobody TI23
收藏Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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https://pdbj.org/mine/summary/7k65
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Hedgehog receptor Patched (PTCH1) in complex with conformation selective nanobody TI23 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ... Authors: Zhang, Y, Bulkley, D.P, Liang, J, Manglik, A, Cheng, Y, Beachy, P.A. Deposit date: 2020-09-18 Release date: 2021-03-17 Last modified: 2024-11-20 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Hedgehog pathway activation through nanobody-mediated conformational blockade of the Patched sterol conduit. Proc.Natl.Acad.Sci.USA, 117, 2020
创建时间：
2020-09-18
