Characterization of plant immunity-activating mechanism by a pyrazole derivative

A newly identified chemical, 4-{3-[(3,5-dichloro-2-hydroxybenzylidene)amino]propyl}-4,5-dihydro-1<i>H</i>-pyrazol-5-one (BAPP) was characterized as a plant immunity activator. BAPP enhanced disease resistance in rice against rice blast disease and expression of a defense-related gene without growth inhibition. Moreover, BAPP was able to enhance disease resistance in dicotyledonous tomato and <i>Arabidopsis</i> plants against bacterial pathogen without growth inhibition, suggesting that BAPP could be a candidate as an effective plant activator. Analysis using <i>Arabidopsis sid2-1</i> and <i>npr1-2</i> mutants suggested that BAPP induced systemic acquired resistance (SAR) by stimulating between salicylic acid biosynthesis and NPR1, the SA receptor protein, in the SAR signaling pathway. BAPP enhanced disease resistance in rice against rice blast disease. Moreover, BAPP was able to enhance disease resistance in dicotyledonous tomato and Arabidopsis.