Association between the genetic loci with altered histone modifications and genes repressed by apicidin.

Genes repressed by 2-fold or greater, in each individual time point in apicidin treated schizonts was determined. In brackets the number of genes associated with an apicidin induced histone modification in at least one locus corresponding to an MOE are shown. For each individual time point, the number of genes with both a change in RNA expression (>2-fold) and associated with an apicidin induced histone modification are shown. Blank boxes refer to P values >0.05. P values represented as bold or in italics correspond to positive and negative correlation respectively.