five

Carbendazim induced genomic instability in yeast

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE112062
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Carbendazim (Methyl benzimidazol-2-ylcarbamate; MBC) is an antimitotic drug used for broad-spectrum fungicide, antineoplastic and mutagen in microbial breeding. Using a customized SNP microarray technology, this work revealed the effect of MBC on genomic instability (loss of heterozygosity, chromosomal rearrangements and aneuploidy) in the diploid yeast Saccharomyces cerevisiae JSC25. By SNP microarrays specific for chromosome 4, we analyzed 40 JSC25-derived mutants treated with MBC to uncover the details of MBC-induced genomic instability.
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2020-08-24
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