Ribosome profiling of G2019S LRRK2 human dopamine neurons
收藏NIAID Data Ecosystem2026-04-25 收录
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资源简介：
G2019S mutaion of LRRK2 is known to increase mRNA translation. We perform ribosome profiling to study defective translation using human dopamine neuron models. Patient-derived human dopamine neurons with G2019S LRRK2 mutation were generated and used. Also a mutation-corrected isogenic pair line was used. Overall design: hDA neurons: 60 days old samples were used.
创建时间：
2020-08-18
