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A microbial derived bile acid acts as GPBAR1 agonist and RORγt inverse agonist and reverses inflammation in inflammatory bowel disease: binding modes retrieved from molecular docking calculations

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NIAID Data Ecosystem2026-05-01 收录
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The interplay between the gut microbiota, bile acids and the immune is a critical determinant in the development of inflammatory bowel disease (IBD). Here, we investigated the binding modes of five bile acid derivatives to RORgt and GPBAR1.

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2024-03-25
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