Crystal structure of the bromodomain of human surface epitope engineered BRD1A in complex with 3D Consortium fragment Ethyl 4,5,6,7- tetrahydro-1H-indazole-5-carboxylate (SGC - Diamond I04-1 fragment screening)

Crystal structure of the bromodomain of human surface epitope engineered BRD1A in complex with 3D Consortium fragment Ethyl 4,5,6,7- tetrahydro-1H-indazole-5-carboxylate (SGC - Diamond I04-1 fragment screening) Descriptor: BROMODOMAIN-CONTAINING PROTEIN 1, ETHYL (5R)-4,5,6,7-TETRAHYDRO-1H-INDAZOLE-5-CARBOXYLATE, SODIUM ION Authors: Pearce, N.M, Fairhead, M, Strain-Damerell, C, Talon, R, Wright, N, Ng, J.T, Bradley, A, Cox, O, Bowkett, D, Collins, P, Brandao-Neto, J, Douangamath, A, Krojer, T, Burgess-Brown, N, Brennan, P, Arrowsmith, C.H, Edwards, E, Bountra, C, von Delft, F. Deposit date: 2015-03-10 Release date: 2015-03-18 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Crystal Structure of the Bromodomain of Human Surface Epitope Engineered Brd1A in Complex with 3D Consortium Fragment Ethyl 4,5,6,7-Tetrahydro-1H-Indazole-5-Carboxylate To be Published

本数据集记录了人表面表位工程化BRD1A溴结构域（bromodomain）与3D联盟片段4,5,6,7-四氢-1H-吲唑-5-羧酸乙酯形成复合物的晶体结构，实验背景为SGC - 钻石光源I04-1片段筛选。
描述项：含溴结构域蛋白1、(5R)-4,5,6,7-四氢-1H-吲唑-5-羧酸乙酯、钠离子。
作者：Pearce, N.M.、Fairhead, M.、Strain-Damerell, C.、Talon, R.、Wright, N.、Ng, J.T.、Bradley, A.、Cox, O.、Bowkett, D.、Collins, P.、Brandao-Neto, J.、Douangamath, A.、Krojer, T.、Burgess-Brown, N.、Brennan, P.、Arrowsmith, C.H.、Edwards, E.、Bountra, C.、von Delft, F.
提交日期：2015年3月10日；发布日期：2015年3月18日；最后更新日期：2024年5月1日。
实验方法：X射线衍射（分辨率1.75埃）。
引用信息：《人表面表位工程化BRD1A溴结构域与3D联盟片段4,5,6,7-四氢-1H-吲唑-5-羧酸乙酯复合物的晶体结构》（待发表）。