Supplementary Table 4 from Combined Proteomic and Genetic Interaction Mapping Reveals New RAS Effector Pathways and Susceptibilities

Results from the single-target sgRNA screen in A549-Cas9 cells. The columns are as follows. Symbol : HUGO gene symbol ; EnsemblID : EnsEMBL identifier ; GeneID : Entrez Gene ID ; GeneInfo : Name of protein encoded by the gene ; Localization : GO cellular localization terms ; Process : GO cellular process terms ; Function : GO molecular function terms ; #Element: Number of identified sgRNAs in sequencing ; Phenotype (pZ) : median log2-fold enrichment of sgRNAS targeting this gene over the course of the experiment ; Tscore : GIT score ; MWU p-Val : p-value of gene depletion or enrichment by Mann-Whitney U test relative to Safe-sgRNAS ; MWU Adjusted Pval : FDR as determined by the Benjamini-Hochberg method.