Single-channel gating in WT and Gαi3−/− myocytes.

Analysis of single-channel gating parameters in ventricular myocytes from WT (n = 7) and Gαi3−/− (n = 6) mice. Recordings with more than one channel were excluded from the analysis. i: unitary current; Ipeak: peak ensemble average current; factive: fraction of traces showing at least one opening; Popen: open probability in active traces; topen: mean duration of openings; τopen: dwell time constant of the open state; tclosed: mean duration between two consecutive openings; τclosed,1: dwell time constant of the fast closed time component; τclosed,2: dwell time constant of the slow closed time component; proportion: ratio of events conferring to either the fast or the slow closed time component; fl: mean latency until the first opening.*: p