Structure of SARS-CoV-2 Mpro mutant (A173V) in complex with Nirmatrelvir (PF-07321332)
收藏Protein Data Bank Japan2024-11-13 更新2026-04-11 收录
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Structure of SARS-CoV-2 Mpro mutant (A173V) in complex with Nirmatrelvir (PF-07321332) Descriptor: (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 Authors: Gajiwala, K.S, Greasley, S.E, Ferre, R.A, Liu, W, Stewart, A.E. Deposit date: 2024-02-29 Release date: 2024-08-07 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.88 Å) Cite: In vitro selection and analysis of SARS-CoV-2 nirmatrelvir resistance mutations contributing to clinical virus resistance surveillance. Sci Adv, 10, 2024
创建时间：
2024-02-29
