Mutation spectrum of IDH1/2 genes in cartilaginous tumors.

NIAID Data Ecosystem2026-03-08 收录

软骨肿瘤

IDH突变

数据链接：

https://figshare.com/articles/dataset/_Mutation_spectrum_of_IDH1_2_genes_in_cartilaginous_tumors_/1479081 数据链接链接失效反馈

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资源简介：

Mutation spectrum of IDH1/2 genes in cartilaginous tumors.

创建时间：

2015-07-10

Mir142 loss unlocks IDH2R140-dependent leukemogenesis through antagonistic regulation of HOX genes. Mir142 loss unlocks IDH2R140-dependent leukemogenesis through antagonistic regulation of HOX genes

白血病分子机制

IDH突变

Acute myeloid leukaemia (AML) is genetically a genetically heterogeneous condition. It was observed that mutations in the micro RNA mir142 co-occurred with mutations in isocitrate dehdrogenase genes I

NIAID Data Ecosystem130

Epidemiological data and PVL of 12 adulthood IDH cases.

胶质瘤临床研究

IDH突变

(XLSX)

NIAID Data Ecosystem70

Modelling data: Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations

药物耐药机制

IDH突变

Modelling structures, settings, and scripts for figure generation accompanying the manuscript: Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations Andrew

Figshare2023-05-31 更新30

Isoform switching as a mechanism of acquired resistance to mutant isocitrate dehydrogenase inhibition

靶向治疗耐药

IDH突变

Targeted next-generation sequencing was performed in patients with IDH1 or IDH2 mutations. Here we describe 4 cases where mutant IDH isoform switching serves as a mechanism of acquired clinical resist

NIAID Data Ecosystem120

Frequency and prognostic value of IDH mutations in Korean patients with cholangiocarcinoma. IDH mutation in cholangiocarcinoma

胆管癌

IDH突变

The molecular profile of cholangiocarcinoma (CC) remains elusive. The prognostic value of isocitrate dehydrogenase (IDH) mutations in CC is controversial, and there have been few relevant studies in A

NIAID Data Ecosystem40

Mutation spectrum of IDH1/2 genes in cartilaginous tumors.

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