Genotyping the 270 HapMap samples for GAIN by Broad. Genotyping the 270 HapMap samples for GAIN by Broad

The Broad Institute Center for Genotyping and Analysis is an NCRR-funded fee-for-service SNP genotyping facility based at MIT (www.broad.mit.edu/genotyping). For the GAIN studies, Broad uses the Affymetrix GeneChip genotyping platform. The first set of studies is being analyzed on the soon-to-be-publicly-released "Human Mapping 500K Array 2.0", which detects 500,000 SNPs, as well as provides information about copy number for 500,000 additional locations across the human genome (www.affymetrix.com). The GAIN studies with African-American samples will be analyzed on the still-in-development "Affy 6.0 chip", which detects about 940,000 SNPs, as well as provides information about copy number for about 900,000 additional locations across the human genome.