Additional file 2 of Genetic-variant hotspots and hotspot clusters in the human genome facilitating adaptation while increasing instability

Additional file 2: Supplementary Table S1. Information on genomic features and markers. Supplementary Table S2. Properties of genetic-variant hotspots and hotspot clusters. Supplementary Table S3. Properties of selection hotspots. Supplementary Table S4. List of cluster-containing genes. Supplementary Table S5. Estimated ages of retrotransposons. Supplementary Table S6. Disease-related variants in GV hotspots and clusters. Supplementary Table S7. Overlap of genetic-variant hotspots or clusters with recombination hotspots. Supplementary Table S8. Autosomal sequences (in base pairs) in different genomic zones and replication phases that overlap with hotspots or clusters. Supplementary Table S9. Enrichment and selection status of hotspots in seven immune system gene loci. Supplementary Table S10. Genomic-feature distributions in genomic regions belonging to different replication-phase segments among 500-kb Genic, Proximal and Distal zones. Supplementary Table S11. Functional annotation of Distal-zone genes.