Summary of patients’ baseline characteristics.
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SD = single dose; RD = repeat dose; SE = standard error.
3Three patients participated in two dose levels of the single dose study and therefore the PGx sample was collected at the first dosing level in which they participated and not the second dosing level. APOE ε4 overall carriage frequency was calculated using the PGx population (n = 15), i.e., patients who participated in more than one dosing level were only taken into account once.
2Six patients participated in part A and re-entered part B. Therefore the pharmacogenetic (PGx) sample was collected when the patients participated in part A and no PGx sample was collected during part B. APOE ε4 overall carriage frequency was calculated using the PGx population (n = 44), i.e., patients who participated in both parts were only taken into account once.
1Values ranged from 20 to 26 for all patients except one, who scored 28.
Summary of patients’ baseline characteristics.
创建时间：
2015-03-19
