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FusionCancer

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国家生物信息中心2025-10-11 更新2025-03-15 收录
下载链接:
http://donglab.ecnu.edu.cn/databases/FusionCancer
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资源简介:
Fusion gene is a chimera product due to the consolidation of two separate genes, which can occur as a consequence of chromosomal structural changes, such as inversion, deletion, amplification or inter-chromosomal/intra-chromosomal translocation [1]. Gene fusion can bring dramatic expression changes compared to previous separate genes because of the regulatory domain displacement, and the resulting chimeric protein-coding transcript will either lose its original function or work into a scabbed protein with functions descended from both its ancestors.
提供机构:
East China Normal University
创建时间:
2018-01-28
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