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ATAC-seq to investigate rewiring the transcriptome of castration-resistant prostate cancer through CDK9 inhibition dataset 1

ChEBI2026-04-08 更新2026-07-12 收录

癌症表观遗传学

前列腺癌治疗靶点研究

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-12986 数据链接链接失效反馈

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资源简介：

ATAC-seq to investigate rewiring the transcriptome of castration-resistant prostate cancer through CDK9 inhibition dataset 1

应用场景：

创建时间：

2026-04-08

癌症表观遗传学

成纤维细胞活化

To understand the driving mechanisms for CAF activation, we performed H3K27ac and H3K4me1 Cleavage Under Targets and Tagmentation (CUT&Tag) analysis in six pairs of NFs and CAFs. At H3K4me1+ sites, we

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Epigenetic dysregulation from chromosomal transit in micronuclei [ATAC-Seq]. Epigenetic dysregulation from chromosomal transit in micronuclei [ATAC-Seq]

癌症表观遗传学

染色质可及性分析

Chromosomal instability (CIN) and epigenetic reprograming are characteristic of advanced and metastatic human cancers, yet whether they are mechanistically linked is unknown. Here we show that missegr

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Epigenomic study identifies a novel mesenchyme homeobox2-GLI1 transcription axis involved in cancer drug resistance, overall survival and therapy prognosis in lung cancer patients

癌症表观遗传学

药物耐药性

Several homeobox-related gene (HOX) transcription factors such as mesenchyme HOX-2 (MEOX2) have previously been associated with cancer drug resistance, malignant progression and/or clinical prognostic

DataONE2020-06-24 更新60

Global 5mC and 5hmC levels in sixteen pairs of HCC and non-HCC samples and two HCC cell lines investigated by UPLC-MS/MS

癌症表观遗传学

甲基化测序

We performed UPLC-MS/MS to investigate global 5mC and 5hmC levels in sixteen pairs of HCC and non-HCC samples and two HCC cell lines (97L and LM6 cells). We found that 5mC and 5hmC were frequently dec

Figshare2016-01-19 更新70

Additional file 4 of Association of expression of epigenetic molecular factors with DNA methylation and sensitivity to chemotherapeutic agents in cancer cell lines

癌症表观遗传学

肿瘤化疗敏感性预测

Additional file 4: Table S4. Significant strong trans- and cis-correlations of GMD expression with methylation of individual probes in the pancancer dataset satisfying p 0.5.

Figshare2021-03-06 更新60

ATAC-seq to investigate rewiring the transcriptome of castration-resistant prostate cancer through CDK9 inhibition dataset 1

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