X-Ray Crystal Structure of Acetylcholine Binding Protein (AChBP) in Complex with N4,N4-bis[(pyridin-2-yl)methyl]-6-(thiophen-3-yl)pyrimidine-2,4-diamine

X-Ray Crystal Structure of Acetylcholine Binding Protein (AChBP) in Complex with N4,N4-bis[(pyridin-2-yl)methyl]-6-(thiophen-3-yl)pyrimidine-2,4-diamine Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine-binding protein, DIMETHYL SULFOXIDE, ... Authors: Kaczanowska, K, Camacho Hernandez, G.A, Harel, M, Taylor, P. Deposit date: 2016-04-02 Release date: 2017-03-08 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.04 Å) Cite: Substituted 2-Aminopyrimidines Selective for alpha 7-Nicotinic Acetylcholine Receptor Activation and Association with Acetylcholine Binding Proteins. J. Am. Chem. Soc., 139, 2017

乙酰胆碱结合蛋白（Acetylcholine Binding Protein, AChBP）与N4,N4-双[(吡啶-2-基)甲基]-6-(噻吩-3-基)嘧啶-2,4-二胺复合物的X射线晶体结构。组分描述：2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、乙酰胆碱结合蛋白、二甲基亚砜（DIMETHYL SULFOXIDE）等。作者：Kaczanowska, K、Camacho Hernandez, G.A、Harel, M、Taylor, P。提交日期：2016-04-02；发布日期：2017-03-08；最后修改日期：2024-11-13。实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率2.04 Å）。引用文献：《取代2-氨基嘧啶类化合物：α7烟碱型乙酰胆碱受体的选择性激活剂及其与乙酰胆碱结合蛋白的相互作用》，发表于《美国化学会志（J. Am. Chem. Soc.）》，第139卷，2017年。