Crystal structure of human PCAF bromodomain in complex with compound SL1126 (compound 12)
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Crystal structure of human PCAF bromodomain in complex with compound SL1126 (compound 12) Descriptor: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Histone acetyltransferase KAT2B, ... Authors: Chaikuad, A, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2015-12-16 Release date: 2016-01-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure-Based Identification of Inhibitory Fragments Targeting the p300/CBP-Associated Factor Bromodomain. J.Med.Chem., 59, 2016
人源PCAF溴结构域与化合物SL1126（化合物12）的共晶结构 描述项：1,2-乙二醇、二甲基亚砜、组蛋白乙酰转移酶KAT2B…… 作者：Chaikuad, A、von Delft, F、Bountra, C、Arrowsmith, C.H、Edwards, A.M、Knapp, S、结构基因组学联盟（Structural Genomics Consortium, SGC） 提交日期：2015-12-16 发布日期：2016-01-13 最后修改日期：2024-01-10 检测方法：X射线衍射（分辨率2.1 Å） 引用文献：《靶向p300/CBP相关因子溴结构域的抑制性片段的基于结构鉴定》，《药物化学杂志》，59卷，2016年
