Impact of mononuclear cell subset depletion on IFNγ producing CD8+ T cells (brain infiltrates).

Six days after infection, cellular infiltrates from the brains of individual mice were prepared and analysed by flow cytometry for the frequency of infiltrating CD8+ cells which produce IFNγ or not upon phorbol myristate acetate (PMA) /Ionomycin restimulation.a n = 4–5 per groupb Significant differences between PbTg infected group and naïve mice, (pc Significant differences between mAb-depleted versus non-depleted PbTg infected mice, (pImpact of mononuclear cell subset depletion on IFNγ producing CD8+ T cells (brain infiltrates).