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The crystal structure of PDE6D in complex to inhibitor-1

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Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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The crystal structure of PDE6D in complex to inhibitor-1 Descriptor: 1-benzyl-2-phenyl-1H-benzimidazole, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta Authors: Gunther, Z, Papke, B, Ismail, S, Vartak, N, Chandra, A, Hoffmann, M, Hahn, S, Triola, G, Wittinghofer, A, Bastiaens, P, Waldmann, H. Deposit date: 2013-03-25 Release date: 2013-05-22 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Small molecule inhibition of the KRAS PDEd interaction impairs oncogenic KRAS signalling Nature, 497, 2013
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2013-03-25
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