Purpose: Physical forces are prominent during tumor progression. However, it is still unclear how they impact and drive the diverse phenotypes found in cancer. Here, we investigate the impact of compr
G protein alpha q and 11 are mutated in 90% of uveal melanoma and they activate the MAPK pathway. Using expression microarray analysis, we identified a unique MEK dependent transcriptional signature w
Transcription profiling of human normal skin, benign and atypical nevi, and early and advanced-stage melanomas to gain insights into the genetic profile of every stage of the melanoma progression path
