Summary of the basal phosphorylation and inhibitor-induced dephosphorylation of inhibitor-resistant or hyperactive LRRK2.

Summary of the basal phosphorylation (Figure 2D–F) and inhibitor-induced dephosphorylation of Ser910, Ser935, and Ser955 (Figure 4). A2016T is an inhibitor-resistant mutant, whereas G2019S and T2031S are hyperactive mutants (Figure 5). Results were classified using plus (+,++,+++) and minus (−) signs as described in Table 1.