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Mitochondrial DNA base editing in vivo via viral DdCBE delivery to somatic cells

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NIAID Data Ecosystem2026-03-13 收录
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We show that delivering the mitochondrial base editor DdCBEs via AAV transduction of somatic cells efficiently produces precise base editing of the intended region. Overall design: Base editing of cytosine to thymine of total DNA of mouse heart and cells.

创建时间:
2022-04-21
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