Data from the ACRIN 6685 Trial HNSCC-FDG-PET/CT

ACRIN-HNSCC-FDG-PET/CT (ACRIN 6685) is a Multicenter Trial of FDG-PET/CT Staging of Head and Neck Cancer and its Impact on the N0 Neck Surgical Treatment in Head and Neck Cancer Patients. The objective of this study was to determine the negative predictive value (NPV) of positron emission tomography (PET)/computed tomography CT for clinically N0 neck based upon pathologic sampling of the neck lymph nodes and to determine PET/CT’s potential to change treatment of the N0 neck.