S1 File - <p> </p>

S1 Fig. Skeletal diagram of fetal mouse. A) Skeletons of fetuses from the control group. B) LPS-induced deformities of the skeleton in mice. C) Skeletons of fetuses from high-dose aspirin treatment group. D) Skeletons of fetuses from low-dose aspirin treatment group. S2 Fig. qPCR was used to detect the relative mRNA expression levels of key inflammatory factors in placental tissues from different groups. GAPDH was served as the internal reference gene, and the relative expression levels of target genes were calculated by the 2 ⁻ ΔΔCt method. (A) Relative mRNA expression level of Tumor Necrosis Factor-α (TNF-α); (B) Relative mRNA expression level of Interleukin-1β (IL-1β); (C) Relative mRNA expression level of Interleukin-6 (IL-6). Differences between groups were compared using an t-test. **P < 0.01 and ***P < 0.001 indicate statistically significant differences between groups. S3 Fig. The original blot and gel (MyD88). S4 Fig. The original blot and gel (β-actin-1). S5 Fig. The original blot and gel (p-IκB). S6 Fig. The original blot and gel (β-actin-2). S7 Fig. The original blot and gel (p-IκB). S8 Fig. The original blot and gel (IκB). S9 Fig. The original blot and gel (β-actin). S10 Fig. The original blot and gel (nuclear NF-κB p65). S11 Fig. The original blot and gel (Histone H3). (ZIP)