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OSI-027 and MRC-5 cells

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NIAID Data Ecosystem2026-03-13 收录
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Hyperoxia promotes time-dependent cell proliferation and the differentiation of lung fibroblasts, as well as the activation of the mTOR signaling pathway. The dual mTORC1/2 inhibitor OSI-027 inhibits the proliferation and differentiation of MRC-5 cells under hyperoxia exposure and is expected to provide a new target for clinical intervention in hyperoxic pulmonary fibrosis.

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2022-08-22
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