PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000666a

PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000666a Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1, methyl (1S,3S,4R)-4-hydroxy-3-[(1S)-1-hydroxypropyl]-2-azabicyclo[2.2.2]octane-2-carboxylate Authors: Keedy, D.A, Hill, Z.B, Biel, J.T, Kang, E, Rettenmaier, T.J, Brandao-Neto, J, von Delft, F, Wells, J.A, Fraser, J.S. Deposit date: 2018-08-30 Release date: 2018-10-10 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.788 Å) Cite: An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering. Elife, 7, 2018PanDDA分析组提交数据——与化合物_FMOOA000666a结合的PTP1B晶体结构。描述项：2-氨基-2-羟甲基丙烷-1,3-二醇、酪氨酸蛋白磷酸酶非受体1型（Tyrosine-protein phosphatase non-receptor type 1）、甲基(1S,3S,4R)-4-羟基-3-[(1S)-1-羟丙基]-2-氮杂双环[2.2.2]辛烷-2-羧酸酯。作者：Keedy, D.A.、Hill, Z.B.、Biel, J.T.、Kang, E.、Rettenmaier, T.J.、Brandao-Neto, J.、von Delft, F.、Wells, J.A.、Fraser, J.S.。提交日期：2018-08-30；发布日期：2018-10-10；最后修改日期：2024-11-13。检测方法：X射线衍射（分辨率1.788 Å）。引用文献：《基于多温度晶体学、片段筛选与共价拴合技术解析PTP1B的扩展变构网络》，《Elife》，7卷，2018年。