Comparison with univariate analysis, sentinel SNP-protein pairs.

Figshare2020-06-03 更新2026-04-28 收录

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Comparison with the univariate two-stage analysis using GEMMA, hits summarized by loci. (XLSX)

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2020-06-03

Multilocus approaches for the measurement of selection on correlated genetic loci

基因组选择估计

统计遗传学方法

The study of ecological speciation is inherently linked to the study of selection. Methods for estimating phenotypic selection within a generation based on associations between trait values and fitnes

DataONE2020-06-24 更新80

Estimated type I error rates for each association testing procedure based on 1,000 samples from the null hypothesis with no risk variants at and subjects.

统计遗传学方法

关联测试错误率评估

The rows highlighted in bold report type I error rates of the procedures after SNP genotype was relabeled to minimize the number of “2-0” or “0-2” flips. Estimated type I error rates for each associat

NIAID Data Ecosystem30

Empirical significance — Percentage of genome-wide transmission test false positives in 10,000 datasets with LD.

统计遗传学方法

基因组关联研究

Proportion of 10,000 datasets simulated under the null hypothesis of no genotyping error and in the presence of LD such that . Columns 2 through 5 display results for various chip sizes when generatin

NIAID Data Ecosystem20

Table_1_eQTLMAPT: Fast and Accurate eQTL Mediation Analysis With Efficient Permutation Testing Approaches.xls

eQTL介导分析

统计遗传学方法

Expression quantitative trait locus (eQTL) analyses are critical in understanding the complex functional regulatory natures of genetic variation and have been widely used in the interpretation of dise

NIAID Data Ecosystem50

Comparison of highly significant marginal association results (P<0.000001) from 4 packages: HLA*IMP:02, HLA*IMP:03, HIBAG (calculated dosages and best guess) and SNP2HLA.

HLA遗传分型

统计遗传学方法

HLA*IMP:01 results from Liu et al. (2012) are shown for comparison. Haplogroups were considered separate (i.e. independent) if predictors remained significant (P< 0.0001) when the top allele from any

NIAID Data Ecosystem20

Comparison with univariate analysis, sentinel SNP-protein pairs.

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