Cryo-EM structure of long form insulin receptor (IR-B) with three IGF2 bound, asymmetric conformation.

Cryo-EM structure of long form insulin receptor (IR-B) with three IGF2 bound, asymmetric conformation. Descriptor: Insulin receptor, Insulin-like growth factor II Authors: An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. Deposit date: 2023-09-10 Release date: 2024-03-27 Last modified: 2024-11-13 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Activation of the insulin receptor by insulin-like growth factor 2. Nat Commun, 15, 2024结合三个胰岛素样生长因子2（IGF2）、呈不对称构象的长型胰岛素受体（IR-B）的冷冻电镜（Cryo-EM）结构。 描述关键词：胰岛素受体、胰岛素样生长因子II 作者：An, W、Hall, C、Li, J、Huang, A、Wu, J、Park, J、Bai, X.C、Choi, E 提交日期：2023-09-10 发布日期：2024-03-27 末次修改日期：2024-11-13 研究方法：电子显微镜（分辨率4.2 Å） 引用文献：胰岛素样生长因子2激活胰岛素受体. Nat Commun, 15, 2024