AGATA: First nationwide molecular screening program in Spain for patients with advanced breast cancer
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE182852
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资源简介：
The SOLTI-1301 AGATA study aimed to assess the feasibility of a multi-institutional molecular screening program to better characterize the genomic landscape of advanced breast cancer (ABC) and to facilitate patient access to matched-targeted therapies in Spain. Between September 2014 and July 2017, 305 patients with ABC from 10 institutions were enrolled. DNA sequencing of 74 cancer-related genes was performed using FFPE tumor samples in three different laboratories with three different gene panels. A multidisciplinary advisory board prospectively recommended potential targeted treatments. The primary objective was to determine the success of matching somatic DNA alteration to an experimental drug/drug class.
创建时间：
2022-02-03
