Zoltan Maliga (2013) CIL:43751, Homo sapiens, epithelial cell. CIL. Dataset
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Shown is a fluorescence microscopy image of a HeLa cell at mitotic metaphase. The cell is stained to reveal DNA (blue), microtubules (red), and the C-terminal portion of the KIF2A protein (green) which is largely confined to the compact chromosomes.
The image is part of a large project to characterize the locations of recombinantly tagged kinesin and myosin genes expressed from human or mouse-derived bacterial artificial chromosomes (BACs) as a resource for cell biology research.
See also: Maliga et al. 2013 A genomic toolkit to investigate kinesin and myosin motor funtion in cells. Nature Cell Biol; published online Feb 2013;DCI:10.1038/ncb2689.
本图展示了一幅 HeLa 细胞有丝分裂中期的荧光显微镜图像。该细胞经染色处理后,其 DNA(蓝色)、微管(红色)以及 KIF2A 蛋白的 C 端(绿色)得以显现,其中 KIF2A 蛋白的 C 端主要局限于紧密的染色体中。该图像是大型项目的一部分,旨在描绘从人类或小鼠来源的细菌人工染色体(BACs)中表达的重组标记肌球蛋白和肌动蛋白基因的位置,以作为细胞生物学研究的资源。此外,可参考 Maliga 等人于 2013 年发表的论文《用于探究细胞中肌球蛋白和肌动蛋白马达功能的基因组工具包》,发表于《自然细胞生物学》杂志,在线发表于 2013 年 2 月;DCI:10.1038/ncb2689。
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CIL



