MicroRNA expression of C. eleagans in space environment. Caenorhabditis elegans

The expression of 228 microRNAs, of the 232 analysed, were also unaffected during 4 and 8 d spaceflight (P>0.05). Overall design: Entire microRNA expression were analyzed using the Filgen® Array miRNA Caenorhabditis elegans 232 probes (Filgen). In the microRNA expression analysis, we compared the expression data between two groups: micro-gravity samples (4 d and 8 d) and controls (4 d and 8 d ground control and 1 G centrifuge onboard ISS). CITATION: The Effectiveness of RNAi in/Caenorhabditis elegans/Is Maintained during Spaceflight Timothy Etheridge, Kanako Nemoto, Toko Hashizume, Chihiro Mori, Tomoko Sugimoto, Hiromi Suzuki, Keiji Fukui, Takashi Yamazaki, Akira Higashibata, Nathaniel J. Szewczyk, Atsushi HigashitaniResearch Article, published 01 Jun 2011 doi:10.1371/journal.pone.0020459