Ivorenolide A, an Unprecedented Immunosuppressive Macrolide from Khaya ivorensis: Structural Elucidation and Bioinspired Total Synthesis
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https://figshare.com/articles/dataset/Ivorenolide_A_an_Unprecedented_Immunosuppressive_Macrolide_from_Khaya_ivorensis_Structural_Elucidation_and_Bioinspired_Total_Synthesis/2457433
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资源简介：
Ivorenolide A (1), a novel 18-membered macrolide
featuring
conjugated acetylenic bonds and five chiral centers, was isolated
from Khaya ivorensis. The structure
of 1 was fully determined by spectroscopic analysis,
single-crystal X-ray diffraction, and bioinspired total synthesis.
Both compound 1 and its synthetic enantiomer 2 showed potent and selective immunosuppressive activity.
创建时间：
2012-12-26
