Cell metabolism is critical for cancer cell transformation and progression. In this study, we have developed a novel method, named Met-express, that integrates a cancer gene co-expression network with
Each reaction in the network was a priori assigned to one of 10 textbook pathways as described in Methods. The pathway assignments are indicated by the color of the reaction vertex in the network. (TR
List of lower and upper bounds of flux identified by flux variability analysis. Flux Variability for ideal, exponential growth with fixed biomass/growth rate and objective metabolite production with t
In comparing the published models, standard metabolic inputs of biomass composition and nutrient uptakes were not counted. For Baroukh et al. [26] EFMs refer to elementary flux modes.