MTR transfers CH3 from MeCbl to HCYS
收藏reactome.org2025-01-15 收录
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Methionine synthase (MTR) mediates the continuous shuttling of cobalamin (Cbl) between two forms, cob(I)alamin and MeCbl. In this half reaction, the methyl group from MeCbl is transferred to homocysteine (HYCS) to form methionine and regenerate cob(I)alamin (Hall et al. 2000; Leclerc et al. 1996).
蛋氨酸合酶(MTR)介导钴胺素(Cbl)在两种形态之间的持续穿梭,即钴(I)胺素和甲基钴胺素(MeCbl)。在此半反应中,甲基钴胺素中的甲基基团被转移至同型半胱氨酸(HYCS),从而形成蛋氨酸并再生钴(I)胺素(Hall 等人,2000年;Leclerc 等人,1996年)。
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