Crystal structure of the epidermal growth factor receptor extracellular region with A265V mutation in complex with epiregulin
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Crystal structure of the epidermal growth factor receptor extracellular region with A265V mutation in complex with epiregulin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 4 of Epidermal growth factor receptor, ... Authors: Hu, C, Leche II, C.A, Stayrook, S.E, Ferguson, K.M, Lemmon, M.A. Deposit date: 2021-01-18 Release date: 2021-11-17 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Glioblastoma mutations alter EGFR dimer structure to prevent ligand bias. Nature, 602, 2022
携带A265V突变的表皮生长因子受体胞外区与上皮调节蛋白(epiregulin)复合物的晶体结构
描述项:2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、表皮生长因子受体亚型4……
作者:Hu, C、Leche II, C.A、Stayrook, S.E、Ferguson, K.M、Lemmon, M.A.
存储日期:2021-01-18
发布日期:2021-11-17
最后修改日期:2024-11-06
实验方法:X射线衍射(3.5 Å)
引用文献:《胶质母细胞瘤突变改变EGFR二聚体结构以消除配体偏向性》,《自然》,602卷,2022年
创建时间:
2021-01-18



