Molecular clustering of the Asian gastric cancer cell lines.

(A) Hierarchical clustering using cell lines with both DNA copy number and mRNA expression data. (B) mRNA expression (mean-centered, normalized) heatmap (upper panel) and copy number (lower panel) of 1,762 putative driver genes from 14 gastric cell lines. (C) ssGSEA pathway enrichment score (mean-centered) heatmap for 380 subtype-specific pathways using 27 gastric cell lines from CCLE. Only selected pathway/genesets are labeled. Color code for mRNA expression: red = high expression, green = low expression. Color code for copy number: green = copy number loss, red = copy number gain, black = normal copy number. Color code for pathway enrichment: red = high enrichment, green = low enrichment.